Choosing the right treatment can feel overwhelming, especially with so much buzz surrounding which one is better Ozempic vs Wegovy. Both medications are FDA-approved GLP-1 receptor agonists that use the active ingredient semaglutide, but they serve slightly different purposes. Ozempic was originally developed for type 2 diabetes management, while Wegovy is primarily prescribed for weight loss. Despite their similarities, they differ in dosage, approved use, and insurance coverage — making it important to understand the details before starting treatment.

If you’re wondering which option might be best for you, this Ozempic vs Wegovy comparison breaks down the key similarities and differences in one place.

Ozempic vs Wegovy comparison Table

Feature	Ozempic	Wegovy
Active Ingredient	Semaglutide	Semaglutide
FDA Approval	Type 2 Diabetes (2017)	Chronic Weight Management (2021)
Primary Use	Lowers blood sugar, reduces risk of heart events, helps with modest weight loss	Designed for significant weight loss in adults with obesity or overweight + comorbidities
Dosage Range	0.25 mg to 2 mg once weekly	0.25 mg to 2.4 mg once weekly
Starting Dose	0.25 mg once weekly	0.25 mg once weekly
Maximum Dose	2 mg weekly	2.4 mg weekly
Effectiveness (Weight Loss)	~12–15 lbs on average in trials	~15% of body weight in trials
Insurance Coverage	Often covered for diabetes	Coverage varies, sometimes not covered for weight loss
Side Effects	Nausea, vomiting, diarrhea, fatigue, possible GI issues (more on this here)	Similar to Ozempic: nausea, vomiting, diarrhea, fatigue; may be more pronounced due to higher dose
Form	Prefilled injection pen	Prefilled injection pen
Brand Owner	Novo Nordisk	Novo Nordisk

Want to learn more? Explore our full range of Ozempic products and Wegovy products here at RocketMeds.